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Current News
Our
recent paper, Opposite Stereochemical Course for
Enzymed-Mediated Alkene Reductions of an Enantiomeric Substrate Pair
(Bougioukou, D.J. and Stewart, J.D., J.
Am. Chem. Soc. 2008, 130,
7655-7658) was featured in the Science Concentrates section of Chemical & Engineering News.
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Jon D. Stewart
Professor, Departments of
Chemistry and Biomedical Engineering
Mailing Address:
127 Chemistry Research
Building
University of Florida
Gainesville, FL
32611
Office 102
Leigh Hall
Office Phone (352) 846-0743
Lab Phone (352)
846-0989
Fax (352)
846-2095
E-mail jds2@chem.ufl.edu
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Ph.D., 1991, Cornell University; B.S.,
M.S. Bucknell University
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Current Research Projects
Our research takes
place where chemistry, biology and nanotechnology meet. It is
highly interdisciplinary work and we collaborate with many other
research groups.
1.
Enzymes as practical catalysts for organic
synthesis. We are developing methods to employ
cofactor-dependent enzymes in stereoselective synthesis. We have
successfully completed biocatalytic routes to several natural products
and continue to expand our synthetic toolbox. Learn more...
2.
Smart, self-disassembling nanostructures for drug delivery.
In collaboration with research teams in the Department of Chemistry (Martin) and
Anesthesiology (Dennis,
Melker and Rogers), we have prepared and covalently capped hollow nano
test tubes with nano corks. We are now learning how to load and
target these structures, then uncap them so that their cargo can be
released inside cells. Learn more...
3.
Understanding a key enzyme in starch biosynthesis. The
economic value of many crops such as corn is directly related to starch
content. In collaboration with a group in Plant Molecular and
Cellular Biology (Hannah),
we are learning how catalysis in this four-subunit enzyme is carried
out and regulated in response to cellular conditions. Learn
more...
 If you
were looking for the host of The Daily Show
and landed here by mistake, this is the "other" Jon
Stewart.
Apart from his being younger, better looking and much wealthier, even
our mothers have a hard time telling the two of us apart.
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Stewart Research Group